33 Immortals Guide | Best S-Tier Perks

Here’s a guide on the best S-Tier Perks you should choose in 33 Immortals.

Game Guide by Ragib Rawnak on Jun 16, 2026

Perks change how you play 33 Immortals. They let you change your character and fight better. You get them slowly as you play. You will have to finish many runs in Inferno to open the whole list. Inferno is just the first mode. Focusing on the right upgrades early makes a big difference.

33 Immortals Guide Killing Enemies

Importance of S-Tier Perks

These are the top choices to grab when you start out. They give you the best boosts immediately. They help you build a foundation before you start worrying about specific weapon setups in 33 Immortals.

33 Immortals Guide Perk Selection Best Perks

Best S-Tier Perks

The Scourge of Omnipotence perk lets you earn more Eternal Shards. You need this currency to make your weapons and other perks stronger. Getting a lot of them early speeds up your progress.

Astute Erudite makes your special co-op skills charge up much faster. Every weapon has a unique power. They are all strong. For example, Daggers create bones, while the Bow deals heavy damage.

Fool's Fate is a perk that simply raises your attack damage. It helps with every weapon in the game. Upgrade it early to drop enemies faster in 33 Immortals.

Fortitude Of Heart is a starting perk that gives you a larger health pool. It helps you survive your first runs, and it's in the style of the Sword.

Soaring Grace is a good early pick to boost your Empathy stat. The higher your Empathy, the more powerful your co-op skills become. It helps them fill up faster and lets you revive down teammates quickly.

Rejuvenated Vigor increases your luck for finding Rare Relics and Epic Relics. Your whole build relies on Relics. Getting better ones makes a massive difference in 33 Immortals.

Also, check our 33 Immortals Review and other guides below: